mobile background

Technology

The Uniz Lab is committed to continuous monitoring

and research to ensure formulation stability for the physical and chemical stability of spicules


Technology

The Uniz Lab is committed to continuous monitoring and research to ensure formulation stability for the physical and chemical stability of spicules

mobile background

Extraction

Fermentation vs. Chemical Extraction

Microbial enzymes and solvents separate spicules in different ways.

Fermentation and chemical extraction are both methods used to isolate desired compounds from natural sources, but they differ in process and principle. Fermentation extraction utilizes microbial enzymes to break down organic matter and generate new substances, whereas chemical extraction uses solvents to dissolve and separate target compounds. Our laboratory has developed a proprietary, eco-friendly method to extract spicules from sponges. This fermentation-based technique breaks down sponge tissue using microbial enzymes to obtain spicules. Compared to chemical extraction, it operates under milder conditions and is recognized as a sustainable alternative. 

Fermentation Extraction

Definition

A method of obtaining useful components by decomposing substances and creating new substances using microorganisms (mainly yeast, mold, and bacteria).


Principle 

Enzymes found in microorganisms break down substrates (raw materials) to produce specific components or change the structure of existing materials to increase their usefulness.


Merit

• It can better utilize the active ingredients of natural ingredients. 

• It can create new bioactive substances. 

• Some fermentation processes help digestion and absorption of food and increase storage capacity. 

• It is environmentally friendly because it does not use chemical solvents.


Disadvantage

• The fermentation process is complex and can take a long time. 

• Controlling the fermentation environment (temperature, pH, nutrients, etc.) is important, and if it fails, it is difficult to obtain the desired substance. 

• The production speed can be slower than chemical extraction.


Example

Manufacturing of fermented foods such as kimchi, yogurt, and cheonggukjang, and enhancing effective ingredients through fermentation of plant extracts, etc.

Chemical Extraction

Definition

A method of dissolving and separating substances using a solvent. 


Principle 

Separation is achieved by taking advantage of the property of the desired substance to dissolve well in a solvent.


Merit

• It can separate substances in a shorter time than fermentation extraction. 

• Generally easy for mass production.


Disadvantage

• There is a possibility of environmental pollution because chemical solvents are used. 

• Harmful substances may be generated. 

• Sometimes, unwanted substances may be extracted along with the desired substances.


Example

Plant extraction using organic solvents, production of petrochemical products, etc.

Extraction

Extraction Method

Microbial enzymes and solvents separate spicules in different ways.

Fermentation and chemical extraction are both methods used to isolate desired compounds from natural sources, but they differ in process and principle. Fermentation extraction utilizes microbial enzymes to break down organic matter and generate new substances, whereas chemical extraction uses solvents to dissolve and separate target compounds. Our laboratory has developed a proprietary, eco-friendly method to extract spicules from sponges. This fermentation-based technique breaks down sponge tissue using microbial enzymes to obtain spicules. Compared to chemical extraction, it operates under milder conditions and is recognized as a sustainable alternative.

Fermentation Extraction

Definition 

A method of obtaining useful components by decomposing substances and creating new substances using microorganisms (mainly yeast, mold, and bacteria). 


Principle

Enzymes found in microorganisms break down substrates (raw materials) to produce specific components or change the structure of existing materials to increase their usefulness.


Merit 

• It can better utilize the active ingredients of natural ingredients. 

• It can create new bioactive substances. 

• Some fermentation processes help digestion and absorption of food and increase storage capacity. 

• It is environmentally friendly because it does not use chemical solvents. 


Disadvantage

• The fermentation process is complex and can take a long time. 

• Controlling the fermentation environment (temperature, pH, nutrients, etc.) is important, and if it fails, it is difficult to obtain the desired substance. 

• The production speed can be slower than chemical extraction. 


Example

Manufacturing of fermented foods such as kimchi, yogurt, and cheonggukjang, and enhancing effective ingredients through fermentation of plant extracts, etc.

Chemical Extraction

Definition 

A method of dissolving and separating substances using a solvent. 


Principle 

Separation is achieved by taking advantage of the property of the desired substance to dissolve well in a solvent. 


Merit 

• It can separate substances in a shorter time than fermentation extraction. 

• Generally easy for mass production.


Disadvantage 

• There is a possibility of environmental pollution because chemical solvents are used. 

• Harmful substances may be generated. 

• Sometimes, unwanted substances may be extracted along with the desired substances.


Example 

Plant extraction using organic solvents, production of petrochemical products, etc.


Differences by Extraction

Features
Fermentation Extraction 
Chemical Extraction 
Efficiency
Varies depending on conditions, can be slow
Generally high and fast
Cost
Cost of media and system construction can be high
Reagents are inexpensive, energy and waste disposal costs may be high
Safety (Operator)
Relatively safe
Caution is required when handling corrosive chemicals
Safety (Product)
No risk of residual chemicals
Risk of residual chemicals
Environmental friendliness
Relatively environmentally friendly
High potential for hazardous waste
Extract purity
Can be pure due to enzyme specificity
Possible for contamination, may require additional purification
Preservation of spicule structure
Structure preservation can be advantageous under mild conditions
Possible for damage under harsh conditions
mobile background


UNIZ LAB          CEO : Youngran Joo 

 2F, Building 2, 381 Aenggogae-ro, Namdong-gu, Incheon, South Korea

Tel :  +82-70-4109-6722           

Fax : +82-32-811-7678 

E-mail : uniz@uniz.co.kr


© UNIZ LAB. All rights reserved..


UNIZ LAB         CEO : Youngran Joo          2F, Building 2, 381 Aenggogae-ro, Namdong-gu, Incheon, South Korea

Tel :  +82-70-4109-6722          Fax : +82-32-811-7678           E-mail : uniz@uniz.co.kr

© UNIZ LAB. All rights reserved.