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Uniz Lab is ahead in technological competitiveness through continuous research and development


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Uniz Lab is ahead in technological competitiveness through continuous research and development

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Frequently Asked Questions

Check out key information that can help you better understand our products.

Views 17

A.

Formulation Instability Caused by Chinese Spicule Refining Methods

Chinese spicules are typically refined using strong acids (hydrochloric acid) or bases (sodium hydroxide) to remove impurities. This method can lead to formulation instability over time—especially after 1 to 3 months of storage—due to the following reasons:


Residual Solvents in Spicule Pores

  • Spicules have a porous structure, and solvents used during refining (HCl or NaOH) may remain trapped inside microcavities.
  • These residues may not affect the formulation immediately but can gradually diffuse or react over time, compromising stability.


Chemical Reactions & pH Shifts Over Time

  • Gradual Release of Residues
    Trapped acid or base residues slowly leach into the aqueous phase of the formulation. This delayed release may not show up in early stability tests but can cause issues after prolonged storage.
  • Continuous pH Changes
    Leached hydrochloric acid lowers pH (acidic), while sodium hydroxide raises it (alkaline). Most cosmetic formulations are designed to remain stable within a mildly acidic to neutral pH range. Deviations can lead to:
  • Emulsifier Breakdown
    Emulsifiers may ionize or deform, destabilizing the emulsion and causing phase separation.
  • Polymer Network Collapse
    Gelling agents like carbomer or acrylate copolymers only maintain viscosity within specific pH ranges. A shift can cause liquefaction or breakdown of the gel.
  • Reactions with Other Ingredients
    Active ingredients or preservatives may become unstable or react undesirably in altered pH conditions.


Internal Stress & Structural Breakdown

  • As residual solvents diffuse into the formulation, they may disrupt the physical and chemical balance at the spicule–formulation interface.
  • This increases internal stress and weakens cohesion around spicules, ultimately leading to structural breakdown of the formulation.


In summary, the use of hydrochloric acid or sodium hydroxide in Chinese spicule refining may leave residual solvents that gradually alter pH and destabilize emulsions or gels—resulting in long-term formulation breakdown.

Views 12

A.

Spicule Powder – Safe Handling Guidelines

Spicules are fine, needle-like powders that may cause irritation if they come into contact with the skin or are inhaled. To ensure safe handling, the following precautions must be observed:


1. Minimize Skin Contact

  • Wear Safety Goggles
    Spicule particles can cause severe pain and irritation if they enter the eyes. Always wear protective goggles.
  • Wear Gloves
    Fine spicule particles may embed into the skin, causing stinging or itching. Use rubber or nitrile gloves to avoid direct contact.
  • Wear Long-Sleeved Clothing
    Minimize exposed skin by wearing long-sleeved workwear.


2. Prevent Inhalation

  • Wear a Dust Mask
    Spicule powder is extremely fine and can easily become airborne. Use a KF94 or industrial-grade dust mask to prevent respiratory irritation.
  • Ensure Proper Ventilation
    Work in well-ventilated areas or use local exhaust systems. Avoid working in enclosed spaces.


3. Maintain a Clean Work Environment

  • Clean Thoroughly After Use
    Remove residual powder using a vacuum cleaner or damp cloth. Avoid dry wiping, which may disperse particles into the air.
  • Prevent Dispersion
    When opening or transferring spicule containers, minimize static electricity and avoid windy or high-vibration areas.
  • Seal Containers Tightly
    After use, close containers securely to prevent contamination and airborne dispersion.


4. Emergency Preparedness

  • Know First Aid Procedures
    If spicules contact skin or eyes, rinse thoroughly with running water and seek medical attention if necessary.
  • Keep Emergency Supplies Nearby
    Equip the workspace with eyewash stations and emergency showers for quick response.
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Optimal Temperature and Timing for Spicule Incorporation in Formulations

To ensure formulation stability and uniform dispersion, spicules must be added at a specific temperature and stage of the process.

  • Ideal Timing: Spicules should be incorporated during the final stage of formulation (cream or gel), after cooling to approximately 30°C.
  • Method of Addition: Add spicules gradually and disperse thoroughly for about 20 minutes to ensure even distribution.


Why Temperature Matters

  • High Temperatures (Above 30°C)
    At elevated temperatures, viscosity decreases, causing spicules to settle more easily. This can lead to uneven distribution and reduced product quality.
  • Low Temperatures (Below 30°C)
    Excessively low temperatures increase viscosity, making it difficult to mix and disperse spicules uniformly. This may result in clumping or poor spreadability, affecting texture and efficacy.


Therefore, the most effective method is to add spicules gradually at around 30°C during the final stage of formulation and disperse them thoroughly to maintain stability and consistency.


Spicule Sedimentation in Liquid Formulations

When spicules are added to liquid formulations, sedimentation may occur due to their higher density compared to the base. This is a natural phenomenon.

To ensure consumers experience consistent texture and efficacy, it is essential to include clear instructions such as “Shake well before use” on the product label.
This helps redistribute settled spicules evenly throughout the formulation before each use.

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A.

Special Handling and Storage Precautions for Brown Spicules

Due to their unique characteristics, brown spicules require extra care during handling and storage. Please follow the guidelines below to ensure safe and effective use:


  • Natural State & Preservative-Free
    Brown spicules are manufactured in their natural form without any added preservatives. While this enhances purity, it also makes them more susceptible to microbial contamination.
  • Sterilization Before Shipment
    Prior to distribution, the product undergoes sterilization to minimize initial microbial load.
  • Recommended Immediate Use After Opening
    Since no preservatives are added, it is strongly recommended to use the product immediately after opening. This helps prevent contamination from external environments and maintains product quality.
    Leaving the product exposed for extended periods may lead to spoilage or microbial growth.


By strictly following these precautions, you can safely and effectively utilize brown spicules while preserving their natural integrity.

Views 9

A.

Spicule Size and Concentration Selection Guide

Spicules are available in various sizes, and selecting the appropriate size and concentration depends on the product’s purpose, usage environment, and application frequency.
UNIZ LAB offers a range of spicule sizes including 100µm, 200µm, 270µm, and 320µm.


1. Criteria for Choosing Spicule Size

• Based on Treatment Goals

  • Deeper Penetration & Stronger Stimulation
    Larger spicules (e.g., 270µm, 320µm) penetrate deeper into the skin and provide stronger stimulation, making them suitable for targeted treatments.
  • Scalp-Specific Use
    The 320µm spicule is optimized for scalp care and is effective in hair and scalp treatment products.
  • Gentle Sensation & General Care
    Smaller spicules (e.g., 100µm, 200µm) offer a gentler feel and are ideal for daily skincare or products for sensitive skin.


• Based on Usage Environment

  • Personal/Home Use
    Products designed for consumer use typically contain smaller spicules (100µm, 200µm) to minimize irritation and enhance ease of use.
  • Professional Use (Esthetic Clinics/Dermatology)
    Professionals may select from a range of spicule sizes depending on the client’s skin condition and treatment goals.
    Larger spicules may be used for intensive care under expert supervision.


2. Importance of Concentration Control

In addition to size, the concentration of spicules in the formulation significantly affects product efficacy and user experience.

• Adjusting Concentration Based on Usage Frequency

  • Daily Use Products
    Should contain low concentrations to avoid overstimulation and maintain skin comfort.
  • Products Used Every 3 Days or Weekly
    May contain slightly higher concentrations for more noticeable effects.
  • Weekly or Professional Treatments
    Can include high concentrations for intensive care, but should be used with caution to avoid irritation.

• Balancing Efficacy and Sensation
Even with the same spicule size, higher concentrations increase stimulation and effectiveness, while lower concentrations offer a gentler feel.
Therefore, size, concentration, and usage frequency must be considered together to determine the final product characteristics.


Explore UNIZ LAB’s diverse spicule sizes to find the optimal solution tailored to your product goals, target users, and application cycle.

Views 14

A.

Spicules Naturally Exit the Skin Over Time

After penetrating the skin, spicules gradually detach and are expelled through the skin’s natural turnover process.
They assist in skin regeneration and typically shed from the surface within approximately two days.

Spicules cannot penetrate deeply into the skin due to its structural characteristics.
Made of silicon dioxide (SiO₂), they do not dissolve inside the skin.
Instead of melting away, they are naturally pushed out as dead skin cells exfoliate.
This makes spicule use safe and reassuring for consumers.

Views 9

A.

Skin Irritation After Using Spicules – Causes and Relief Methods


1. Micro-Needle-Induced Skin Irritation

Spicules are micro-needle structures made of natural silica extracted from marine sponges.
When applied to the skin, they penetrate and form countless micro-channels.
This process may cause slight wounds and physical stimulation, leading to stinging, itching, or redness—a natural reaction during skin regeneration.


2. Natural Skin Recovery Response (Inflammation)

As spicules penetrate the skin, the body recognizes them as foreign intruders and initiates a healing response.
Immune cells become activated, and a mild, controlled inflammatory reaction may occur, resulting in redness and itching.


3. Increased Skin Sensitivity

Spicule use may temporarily weaken the skin barrier, making it more sensitive to external stimuli like UV rays.
This heightened sensitivity can amplify symptoms such as redness or itching.


4. Overuse or High Concentration

Using high-concentration spicule products too frequently can lead to excessive stimulation.
This may worsen symptoms like redness, itching, and stinging, especially for those with sensitive skin, atopic dermatitis, or rosacea.


5. Allergic Reactions

In rare cases, allergic reactions to certain ingredients in spicule products may cause redness, itching, or swelling.


Relief Methods


1. Focus on Soothing and Moisturizing

  • Cold Compress: Apply a cool pack or chilled towel to reduce skin temperature and calm irritation.
  • Use gentle moisturizers: Choose products rich in ceramides, hyaluronic acid, or panthenol to restore the skin barrier.
  • Apply calming ingredients: Look for formulas with centella asiatica (cica), aloe vera, or panthenol.


2. Minimize Irritation

  • Gentle cleansing: Use lukewarm water and mild cleansers for 2–3 days.
  • Avoid forced exfoliation: Let dead skin shed naturally—don’t rub or peel manually.
  • Avoid intense activities: Refrain from vigorous exercise, saunas, alcohol, or smoking for 2–3 days.
  • Limit makeup: Avoid makeup on the day of use; apply lightly from the next day.


3. Strict Sun Protection

  • Apply SPF 30+ sunscreen thoroughly before going outside.
  • Avoid direct sunlight, and use sunscreen indoors if exposed to windows.


4. Adjust Product Usage

  • Start with low concentrations to monitor skin response.
  • Limit frequency to 1–2 times per week initially, then gradually increase.


5. Consult a Dermatologist

If symptoms like itching, redness, stinging, or oozing persist for more than a day or worsen, seek professional help.
Those with pre-existing skin conditions should consult a specialist promptly.


Spicules can support skin regeneration, but reactions vary by skin type and condition.
Use them cautiously, and stop immediately if adverse reactions occur—then consult a dermatologist.

Views 10

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Low-Purity Spicules: Risks and the Importance of High Purity

Some manufacturers may collect residual materials left over from the refining process and sell them as low-purity spicules at a lower cost. However, such low-grade spicules can pose the following risks:


Problems with Low-Purity Spicules

  • Formulation Instability
    Impurities other than spicules can negatively affect cosmetic formulations, leading to reduced product stability and efficacy.
  • Inconsistent Quality
    As by-products of the refining process, low-purity spicules often vary in quality from batch to batch, making it difficult to maintain product consistency.


Recommendation: Use High-Purity Spicules

For these reasons, we recommend using high-purity spicules with controlled concentrations rather than low-purity alternatives. High-purity spicules offer the following advantages:

  • Stable Quality
    Consistent and high-grade spicules help maximize product stability and performance.
  • Better Compatibility with Formulations
    Fewer impurities mean better synergy with cosmetic bases and reduced risk of unwanted side effects.


At UNIZ LAB, we prioritize product safety and quality above all else. We are committed to providing only the finest raw materials.
If you have any questions about high-purity spicules or would like further information, please feel free to reach out anytime!

Views 8

A.

Spicule Fermentation Refining Method: UNIZ LAB’s Core Values

At UNIZ LAB, we have not filed a patent for our spicule fermentation refining method. This technique is the result of years of accumulated experimentation and research, forming our proprietary know-how and core technology.

While fermentation requires more time and cost compared to chemical methods, we remain committed to this approach because of three key values:


  • 1. Cosmetic Stability
    The fermentation process enhances ingredient stability, minimizing product degradation and helping maintain optimal quality throughout its shelf life.
  • 2. Skin Safety for Consumers
    By reducing the use of unnecessary chemical agents and refining spicules through a nature-friendly process, we offer products that are safe even for sensitive skin types.
  • 3. Environmental Sustainability
    We pursue sustainable practices that minimize environmental impact and contribute to eco-conscious innovation.


For these reasons, we choose not to disclose the details of our fermentation refining method to the public.

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Division

Products

Usage

Types

Spicule size/Spicule Content(%)

1

Personal

Mild

Daily

Cream

100/0.5~1

2

Personal

Brighting/Whitening

Weekly

Cream

200/1~3

3

Personal

Wrinkle

Weekly

Cream

270/1~3

4

Personal

Baggy Eye

Every 3day

Cream

100/0.3~1

5

Personal

Age Spot

Every 3day

Cream

200/0.5~1

6

Personal

Trouble Spot

Every 3day

Cream

200/0.5~1

7

Personal

Cellulite

Weekly

Cream

100/1~3

8

Personal

Thin Cheek

Weekly

Cream

270/1~3

9

Personal

Neck Wrinkle

Every 3day

Cream

100/0.5~1

10

Personal

피부장벽개선

Weekly

Cream

100/0.5~2

11

Personal

Striae Distensae Improvement

Every 3day

Cream

200/0.5~1

12

Personal

Eyebrow nutrition

Weekly

Cream

270/1~3

13

Personal

Back Acne

Weekly

Gel

100-0.5~1.5

14

Personal

Acne

Weekly

Gel

270/1~3

15

Personal

Acne

Daily

Gel

200/0.5~1

16

Personal

Blackhead/Whitehead

Weekly

Gel

270/1~3

17

Personal

Pore Reduction

Weekly

Gel

270/1~3

18

personal

Acne Scar vanish

Weekly

Gel

270/1~3

19

Personal

Hair Loss(Men)

Weekly

Liquid

320-1~3

20

Personal

Hair Loss(Women)

Weekly

Liquid

320/1~3

21

Home Care

Brighting/Whitening

Weekly

Powder

200/1~3

22

Home Care

Wrinkle

Weekly

Powder

270/1~3

23

Home Care

Acne

Weekly

Powder

270/1~3

24

Professional

ALL IN ONE

Weekly

Cream

270/3~5

25

Professional

All IN ONE

Weekly

Powder

270/3~5

26

Professional

Hair Loss

Weekly

Liquid

320/3~5

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Explanation of Spicule Length Variability

Spicule length is not uniform. This is because spicules serve as the skeletal structure of sponges, and their length naturally varies depending on the sponge’s growth stage.

Sponges are living organisms, and as they grow, their spicules form and develop alongside them.
Each spicule may have slightly different lengths depending on the time of formation and environmental conditions during growth.
This variability is a natural physical characteristic of spicules, which are derived from biological sources.

Views 11

A.

Post-Spicule Skincare Guide for Optimal Results

Spicules are effective for promoting skin turnover and enhancing absorption of active ingredients, but proper aftercare is essential to maintain healthy skin. Here are key tips to help your skin stay in top condition after using spicules:


1. Hydration Is the Foundation

After using spicules, your skin may feel temporarily sensitive or dry.
Apply a generous amount of moisturizer containing ingredients like ceramides, hyaluronic acid, or panthenol to strengthen the skin barrier and soothe irritation.
A strong moisture barrier helps prevent water loss and shields the skin from external stressors.


2. Use Mist Frequently to Stay Hydrated

If your skin feels dry, spritz a hydrating mist throughout the day.
Choose alcohol-free mists with soothing ingredients.
Mists with moisturizing agents are more effective than plain water in calming and hydrating the skin.


3. Sun Protection Is Absolutely Essential

After spicule use, your skin becomes more sensitive to UV rays.
To prevent damage or pigmentation, apply sunscreen thoroughly before going outside.
Use products with SPF 30+ and PA+++, and reapply every 2–3 hours.
Physical (mineral) sunscreens are gentler on sensitive skin.


4. Gentle Care During Exfoliation

Mild exfoliation may occur over several days after using spicules.
This is a natural part of the skin renewal process—don’t worry!
Avoid forcibly peeling or scrubbing the skin.
Instead, wash gently with lukewarm water and let the dead skin shed naturally.
Avoid using exfoliating towels or harsh scrubs.


By following these care tips, you’ll maximize the benefits of spicules and support your skin’s health and glow.

Views 9

A.

Spicules – Use Them Properly, Not Frequently!

The key to effective spicule skincare is not frequent use, but correct usage based on concentration. Overuse can lead to skin damage, while proper intervals help maximize benefits.


1. Low-Concentration Spicules (0.1–0.3%) – Safe for Daily Use

Products containing 0.1% to 0.3% spicules are suitable for daily use.
They gently stimulate the skin, support healthy turnover cycles, and enhance absorption of active ingredients.
Think of it like light daily exercise—consistent use can improve overall skin condition.


2. Medium-Concentration Spicules (Above 0.3%) – Avoid Daily Use

Products with more than 0.3% spicules should not be used every day.
Spicules work by creating micro-injuries to trigger regeneration.
Using high concentrations daily may cause cumulative damage, weaken the skin barrier, and increase sensitivity.
Always follow the manufacturer’s recommended usage cycle.


3. High-Concentration / Professional Spicules (1% or More) – Minimum One Week Recovery

Spicule products with 1% or more are typically used in dermatology clinics or esthetic treatments.
They must be applied under professional guidance and require at least one week of recovery time between uses.
These potent formulas deeply stimulate turnover and regeneration, so the skin needs time to heal.
Using them too frequently can lead to irritation or skin trouble.


Final Note

Always tailor your spicule usage strategy to the product’s concentration and your skin’s condition.
Following the recommended cycle is the fastest path to healthy, radiant skin! 

Views 9

A.

Exfoliation After Using Spicules – A Normal Skin Renewal Process!

After using spicule-based products, some exfoliation may occur. But don’t worry—this is a normal and expected effect. As spicules penetrate the skin, they promote the shedding of old keratinized cells and stimulate the production of new skin cells. It's like pruning old branches to make way for fresh sprouts—a sign that your skin is regenerating healthily.


Differences in Exfoliation by Skin Type

The level of exfoliation can vary based on skin type:

  • Oily Skin
    Tends to have more active sebum production and a thicker keratin layer. As a result, those with oily skin may experience more noticeable exfoliation after using spicules. This is a sign that the thick keratin buildup is being effectively removed.
  • Dry Skin
    Compared to oily skin, dry skin may show less visible exfoliation. However, even if not obvious, regeneration is still actively occurring beneath the surface.


Proper Care During Exfoliation

The most important thing during exfoliation is to avoid forcibly removing peeling skin. Scratching or using exfoliating towels can damage your skin by causing unnecessary irritation.

  • Gentle Cleansing with Lukewarm Water
    If you notice flaking skin, wash gently with lukewarm water to allow it to fall off naturally—like soaked paper softly sliding away.
  • Focus on Moisturization
    Your skin may feel drier than usual during this period, so it’s crucial to maintain moisture and support your skin barrier with proper hydration.


Exfoliation after spicule use is part of the process toward brighter and healthier skin. Just follow the right care techniques to assist your skin’s natural renewal! 

Views 12

A.

Spicules Cannot Be Considered Vegan

Here’s why:

  • Animal-Derived Source
    Spicules are extracted from sea sponges, which are classified as animals—even though they may resemble plants in appearance. Biologically, sponges belong to the animal kingdom.
  • Conflict with Vegan Principles
    Veganism is based on the principle of avoiding all forms of animal exploitation and the use of animal-derived ingredients. Even though the primary component of spicules is an inorganic substance (silica), their origin being animal-based disqualifies them from vegan categorization.


Therefore, products containing spicules cannot be classified as vegan items

Views 12

A.

Spicule Extraction Source: Freshwater Sponge

Spicules are micro-needle structures gaining attention in both the beauty and medical fields. They originate from the humble yet ancient organism: the sponge. Sponges are considered one of the earliest multicellular animals to appear on Earth, holding remarkable evolutionary history.


1. Biological Classification & Features of Sponges

  • First Animals: Sponges likely emerged before the Cambrian Period, over 600 million years ago. Although they lack complex organs or tissues, they’ve survived using a unique filter-feeding method.
  • Wide Habitats: Found in oceans and freshwater across the globe, over 8,000 species have been identified. They are sessile organisms, attaching themselves to rocks or other surfaces.
  • SpongeBob Inspiration: The popular cartoon character “SpongeBob” was inspired by the quirky form and structure of real sponges!


2. Source of Cosmetic Spicules: Freshwater Sponges

Not all sponges are used for cosmetic or medical purposes. The ones employed in beauty products are typically extracted from freshwater sponges.

  • Characteristics of Freshwater Sponges: These organisms have evolved in a distinctly different environment from marine sponges. They only survive in exceptionally clean, unpolluted freshwater conditions.
  • Main Component – Silica (SiO₂): Spicules are primarily made of silica, which creates hard, glass-like microstructures. These fine needles penetrate the skin surface, enhancing absorption of active ingredients and promoting skin regeneration.


3. Freshwater Sponges & Water Quality

Freshwater sponges do more than supply spicules—they’re important biological indicators of water quality.

  • Indicator of Clean Water: They can only survive in pristine aquatic environments. Their presence implies excellent water quality and healthy ecosystems.
  • Environmental Importance: Because of their sensitivity to pollution, they’re often used in ecological research for monitoring water quality and biodiversity.


In summary, spicules are naturally derived materials sourced from ancient freshwater sponges—organisms that thrive only in the cleanest environments. Their fascinating origin not only adds scientific credibility but also a touch of nature-inspired elegance to skincare.

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UNIZ LAB          CEO : Youngran Joo 

 2F, Building 2, 381 Aenggogae-ro, Namdong-gu, Incheon, South Korea

Tel :  +82-70-4109-6722           

Fax : +82-32-811-7678 

E-mail : uniz@uniz.co.kr


© UNIZ LAB. All rights reserved..


UNIZ LAB         CEO : Youngran Joo          2F, Building 2, 381 Aenggogae-ro, Namdong-gu, Incheon, South Korea

Tel :  +82-70-4109-6722          Fax : +82-32-811-7678           E-mail : uniz@uniz.co.kr

© UNIZ LAB. All rights reserved.