Uniz Lab Production System | The Science of the Process That Perfects Speckle Quality

An optimized production line ensures consistent production of high-quality raw materials, plays a key role in improving cost efficiency in the manufacturing process, and ultimately in building consumer trust. An efficient production system systematically manages all processes from the receipt of raw materials to the shipment of finished products, minimizing defect rates and maximizing productivity. In addition, strict quality control and hygiene management ensure product safety, allowing customers to use them with confidence.

We conduct various product tests to evaluate quality assurance (QA) and quality control (QC), raw material verification, process control, purity, stability, safety, and efficacy of products, suitability tests to check the interaction between packaging materials and contents, stability tests to observe product changes over time, microbial tests to check for the presence of harmful microorganisms, sensory evaluations to evaluate the color, scent, and texture of products, human patch testing (HRIPT) to evaluate skin irritation and allergic reactions, and clinical trials to prove the efficacy of products.

Freshwater sponges inhabit rivers and lakes at depths ranging from 1 to 5 meters. To harvest high-quality sponges for commercial use, meticulous procedures such as site management, collection, and drying are essential. We operate large-scale farms across various regions of the world, enabling consistent and sustainable sponge harvesting. The collection season for freshwater sponges is limited to August through November and is highly influenced by climatic conditions. As the world’s largest manufacturer of spicules, UNIZ Lab utilizes over 30 tons of sponge annually, with a maximum monthly spicule production capacity of 1,500 kg. To ensure supply stability in the face of unexpected natural disasters, we maintain a safety stock of approximately 40 tons of sponge.

An optimized production line ensures consistent production of high-quality raw materials, plays a key role in improving cost efficiency in the manufacturing process, and ultimately in building consumer trust. An efficient production system systematically manages all processes from the receipt of raw materials to the shipment of finished products, minimizing defect rates and maximizing productivity. In addition, strict quality control and hygiene management ensure product safety, allowing customers to use them with confidence.

We conduct various product tests to evaluate quality assurance (QA) and quality control (QC), raw material verification, process control, purity, stability, safety, and efficacy of products, suitability tests to check the interaction between packaging materials and contents, stability tests to observe product changes over time, microbial tests to check for the presence of harmful microorganisms, sensory evaluations to evaluate the color, scent, and texture of products, human patch testing (HRIPT) to evaluate skin irritation and allergic reactions, and clinical trials to prove the efficacy of products.

Freshwater sponges inhabit rivers and lakes at depths ranging from 1 to 5 meters. To harvest high-quality sponges for commercial use, meticulous procedures such as site management, collection, and drying are essential. We operate large-scale farms across various regions of the world, enabling consistent and sustainable sponge harvesting. The collection season for freshwater sponges is limited to August through November and is highly influenced by climatic conditions. As the world’s largest manufacturer of spicules, UNIZ Lab utilizes over 30 tons of sponge annually, with a maximum monthly spicule production capacity of 1,500 kg. To ensure supply stability in the face of unexpected natural disasters, we maintain a safety stock of approximately 40 tons of sponge.

GMP (Good Manufacturing Practice) is a set of regulations that define standards for manufacturing and quality control across various industries, including pharmaceuticals, medical devices, and food. Compliance with GMP is essential to ensure consistent product quality and safety, with detailed requirements tailored to each sector. In the cosmetics industry, GMP encompasses all aspects of production—from facilities, equipment, and personnel to raw materials, manufacturing processes, packaging, storage, and documentation. Adhering to these standards minimizes the risk of contamination, degradation, and quality loss. Our laboratory is currently undergoing GMP guideline assessment. This initiative aligns with global standards and contributes to public health protection by preventing the deterioration of cosmetic ingredients.

Strict Hygiene and Cleanliness Management

Ensuring product safety is of utmost importance.

Spicule Raw Material Procurement and Preprocessing

This is a critical step in obtaining high-quality spicules. Spicules are primarily extracted from freshwater and marine sponges, and the extraction process must include purification to remove impurities and organic substances that may cause allergic reactions.

Incoming Raw Material Inspection

Another key mechanism of microneedling is its ability to significantly enhance Transdermal Drug Delivery (TDD). Micro-needles physically penetrate the stratum corneum—the outermost barrier of the skin—creating numerous microchannels. Normally, the stratum corneum limits the penetration of large or hydrophilic molecules (some sources cite less than 0.3%), but the microchannels formed by MTS bypass this barrier, allowing active ingredients such as vitamins, growth factors, hyaluronic acid, tranexamic acid (TXA), PDRN, and exosomes to effectively reach the deeper layers of the epidermis and dermis. We inspect the purity, size, and morphology of spicule raw materials, along with quality checks for other ingredients and components.

Quality Control During Manufacturing

We monitor environmental conditions (temperature, humidity, etc.) at each production stage and regularly check mixing ratios and blending status. Intermediate products undergo quality tests for pH, viscosity, and appearance, with strict measures in place to prevent microbial contamination.

Finished Product Quality Testing

Final cosmetic products are evaluated through sensory tests for appearance, color, scent, and texture, as well as physicochemical tests for pH, viscosity, and specific gravity. We also conduct microbial safety tests, stability tests under various temperature and humidity conditions, active ingredient content analysis (including spicules), and—when necessary—skin irritation and allergy potential assessments.

GMP Compliance GMP (Good Manufacturing Practices) Compliance GMP (Good Manufacturing Practice) is a set of regulations that define standards for manufacturing and quality control across various industries, including pharmaceuticals, medical devices, and food. Compliance with GMP is essential to ensure consistent product quality and safety, with detailed requirements tailored to each sector. In the cosmetics industry, GMP encompasses all aspects of production—from facilities, equipment, and personnel to raw materials, manufacturing processes, packaging, storage, and documentation. Adhering to these standards minimizes the risk of contamination, degradation, and quality loss. Our laboratory is currently undergoing GMP guideline assessment. This initiative aligns with global standards and contributes to public health protection by preventing the deterioration of cosmetic ingredients.

Strict Hygiene and Cleanliness Management

Ensuring product safety is of utmost importance.

Spicule Raw Material Procurement and Preprocessing

This is a critical step in obtaining high-quality spicules. Spicules are primarily extracted from freshwater and marine sponges, and the extraction process must include purification to remove impurities and organic substances that may cause allergic reactions.

Incoming Raw Material Inspection

Another key mechanism of microneedling is its ability to significantly enhance Transdermal Drug Delivery (TDD). Micro-needles physically penetrate the stratum corneum—the outermost barrier of the skin—creating numerous microchannels. Normally, the stratum corneum limits the penetration of large or hydrophilic molecules (some sources cite less than 0.3%), but the microchannels formed by MTS bypass this barrier, allowing active ingredients such as vitamins, growth factors, hyaluronic acid, tranexamic acid (TXA), PDRN, and exosomes to effectively reach the deeper layers of the epidermis and dermis. We inspect the purity, size, and morphology of spicule raw materials, along with quality checks for other ingredients and components.

Quality Control During Manufacturing

We monitor environmental conditions (temperature, humidity, etc.) at each production stage and regularly check mixing ratios and blending status. Intermediate products undergo quality tests for pH, viscosity, and appearance, with strict measures in place to prevent microbial contamination.

Finished Product Quality Testing

Final cosmetic products are evaluated through sensory tests for appearance, color, scent, and texture, as well as physicochemical tests for pH, viscosity, and specific gravity. We also conduct microbial safety tests, stability tests under various temperature and humidity conditions, active ingredient content analysis (including spicules), and—when necessary—skin irritation and allergy potential assessments.

Optimized Production and Quality System

GMP Compliance